Live confocal movie demonstrating the conversion of healthy mature adult leukocytes to a stem cell stage following initiation of the retrodifferentiation process. The movie duration is 12 hours with a clip taken every 3 minutes. This movie demonstrates the loss of mature marker, CD19, on differentiated cells (stained green). Upon induction of the process of retrodifferentiation, the green stain disappears from the surface of the cell and the haematopoietic stem cell marker, CD34 (red stained), progressively increases on the surface of the cells; the hallmark of reverting back to a stem cell stage.

Cardiac

Real-Time movie demonstrating beating cardiomyocytes exhibiting spontaneous contraction and elongation. The contraction of cardiomyocytes is often synchronous among small groups of cells visible within the microscopic field and, with simultaneous rotation and contraction of the cells, a ‘torsional’ contractile appearance can be observed.